منابع مشابه
Development and cellular localization of rat testicular aromatase activity.
Oestradiol secretion by isolated Leydig cells, Sertoli cells, myoid cells, germinal cells and liver cells from rats of different ages was measured by a validated radioimmunoassay technique. All cells, except germinal cells and liver cells, produced oestradiol when incubated in the presence of testosterone. Sertoli cells from 7- and 10-day-old rats and from prenatally irradiated adult rats were ...
متن کاملEffects of incubation temperature and estrogen exposure on aromatase activity in the brain and gonads of embryonic alligators.
During embryogenesis, incubation temperature and the hormonal environment influence gonadal differentiation of some reptiles, including all crocodilians. Current evidence suggests that aromatase, the enzyme that converts androgens to estrogens, has a role in sexual differentiation of species that exhibit temperature-dependent sex determination (TSD). During the temperature-sensitive period (TSP...
متن کاملThe regulation of androgen and estrogen formation in fetal gonads
Several aspects of the functional development of the testis and ovary have been characterized in the fetal rabbit. First, the capacity of the fetal ovary to form 17p-estradiol develops at the same time in embryogenesis as the onset of testosterone formation in the fetal testis. Second, both fetal ovaries and testes have the capacity to form these steroid hormones from cholesterol de novo. Third...
متن کاملBmp7 regulates germ cell proliferation in mouse fetal gonads.
Relatively little is known regarding the signals that regulate the proliferation and sex-specific development of germ cells during mammalian fetal gonad differentiation. Members of the bone morphogenetic protein (BMP) family have been identified as key regulators of germ cells in the Drosophila gonad. Here we show that in mice Bmp7 is expressed in gonads of both sexes and is required for germ c...
متن کاملA study of meiosis in chimeric mouse fetal gonads.
The influence of somatic environment on the onset and progression of meiosis in fetal germ cells was studied in chimeric gonads produced in vitro by dissociation-reaggregation experiments. Germ cells isolated from testes or ovaries of 11.5-13.5 days post coitum (dpc) CD-1 mouse embryos were loaded with the fluorescent supravital dye 5-6 carboxyfluorescein diacetate succinimyl ester (CFSE) and m...
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ژورنال
عنوان ژورنال: Reproduction
سال: 1989
ISSN: 1470-1626,1741-7899
DOI: 10.1530/jrf.0.0870355